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Binding-Site Purification of Actives (B-SPA) enables efficient large-scale progression of fragment hits by combining multi-step array synthesis with HT Crystallography

Thereafter, medium was replaced by new medium with or without ghrelin at concentrations of 10 nM, 100 nM, and 1 M and cells were incubated for 24 h

Reconstituted: Refrigerate at 28 C (35.646.4 F) , protected from light, and use within about 14 days

PMCID: PMC8419463

Beyond basic pricing, factors like peptide integrity, manufacturing standards, and supply chain reliability are paramount for a successful B2B partnership

10.1007/s00204-013-1012-x Arch