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Poor SH, Weissgerber G, Adams CM, Bhatt H, Browning DJ, Chastain J, Ciulla TA, Ferriere M, Gedif K, Glazer LC, Joondeph BC, Normand G, Sheth V, Watters C, Grosskreutz CL

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Small intestinal bacterial overgrowth (SIBO) has been anecdotally reported in semaglutide users, potentially triggered by the slow intestinal transit that GLP-1 agonists create

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These were generally mild and not classified as serious adverse events, but they establish that retatrutide does have a measurable effect on cardiac rhythm beyond simple rate increase