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Garca-Gmez R, Bustelo XR, Crespo P (2018) Protein-protein interactions: emerging oncotargets in the RAS-ERK pathway
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The transformation of monocyte/macrophages into foam cells, is the hallmark of atherogenesis
Common side effects are primarily gastrointestinal: Nausea (most common, typically improves with titration) Diarrhea or constipation Abdominal discomfort Reduced appetite (intended therapeutic effect) Serious but rare adverse events include: Pancreatitis Gallbladder disease (especially during rapid weight loss) Boxed warning for thyroid C-cell tumors (observed in rodent studies, not confirmed in humans) From $299 Why These Compounds Do Not Interact Drug interactions occur through several mechanisms: receptor competition, enzyme competition, altered absorption, or pharmacodynamic overlap
DPP-4 inhibitors significantly raise 25(OH)-D levels in serum, promoting bone growth and remodeling [136]
