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USA 112 , 28882893 (2015)

In terms of one-carbon metabolism support, intermediate metabolites of the SSP participate in one-carbon unit transfer primarily through serine hydroxymethyltransferase 2 (SHMT2), supplying raw materials for purine and pyrimidine biosynthesis as well as DNA methylation

Imbernon M, Saponaro C, Helms HCC, Duquenne M, Fernandois D, Deligia E, Denis RGP, Chao DHM, Rasika S, Staels B, Pattou F, Pfrieger FW, Brodin B, Luquet S, Bonner C, Prevot V

Children with chronic otitis media with effusion given glutathione as a nasal aerosol had improvement in 67% of patients, versus only 8% of controls

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