In a case-control study involving smokers with normal lung function, COPD, and lung cancer (COPD subtype), it was found that the GG genotype of the rs1489759 HHIP SNP and the CC genotype of the rs2202507 GYPA SNP exhibited a protective effect against both COPD (OR 0.59, p = 0.006 for HHIP and OR = 0.65, p = 0.006 for GYPA) and lung cancer (OR = 0.70, p = 0.05 for HHIP and OR = 0.70, p = 0.02 for GYPA) [139]
Evidence Snapshot The STEP trials demonstrated significant weight reduction with semaglutide, with gastrointestinal side effects most prominent during dose escalation. Long-term micronutrient outcomes were not primary endpoints
Key Facts: Liraglutide slowed cognitive decline by 18% in mild Alzheimers patients
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doi: 10.1016/J.IJBIOMAC.2022.11.132 92 KaurJ.RajkhowaR.AfrinT.TsuzukiT.WangX
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