With anti-A and anti-tau therapies entering AD practice, GLP-1RAs may be most effective in combination, targeting metabolic and inflammatory pathways that complement direct amyloid or tau lowering
Congenital melanotic macules of the tongue ( congenital lingual melanotic macules ) is voor het eerst beschreven in 2003 door Dohil et al
Interestingly, sphingolipid metabolism emerged as a common pathway perturbed in the three mutants, although the number of genes in the clusters varied among the three mutants (Supplementary Fig
These patients may differ in baseline characteristics, behavioral factors, or comorbidity burden compared with those achieving optimal surgical outcomes, introducing potential selection bias inherent to retrospective designs
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