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Neoroscience 2000

For the broader pipeline context around these compounds, see our investigational peptide drugs for diabetes and obesity reviews 2019-2026 guide

While the clinical translation is still in its early days, the mechanistic rationale is compelling, and the preclinical evidence is impressive

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Desbouys L, Mjean C, De Henauw S, Castetbon K (2020) Socio-economic and cultural disparities in diet among adolescents and young adults: a systematic review

In blood pressure studies, the peptide did not affect basal blood pressure but counteracted both L-NAME-induced hypertension and L-arginine-induced hypotension