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Additionally, cardiovascular and metabolic benefits observed at therapeutic doses might be partially retained at lower doses, though this remains speculative without dedicated dose-finding studies
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The South African Health Products Regulatory Authority (SAHPRA) has approved only three injectable medicines containing GLP1s: Novo Nordisks liraglutide and its predecessor semaglutide, and Eli Lillys tirzepatide
Retatrutide follows a titration schedule similar to other GLP-1 medications, starting low and gradually increasing to minimize gastrointestinal side effects
Conclusion: Embarking on a medical weight loss journey with GLP-1 therapies involves navigating various aspects, and constipation is one consideration that shouldn't be overlooked
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