Potential Mechanisms Behind Numbness During Mounjaro Treatment When patients experience numbness whilst taking Mounjaro, understanding the potential underlying mechanisms helps guide appropriate investigation and management
10.1534/genetics.119.302939 [DOI] [PMC free article] [PubMed] [Google Scholar] Izadi A., Ebrahimi S., Shirazi S., Taghizadeh S., Parizad M., Farzadi L., et al
2018;90(15):e1283e1290
Multiple interconnected pathways play a crucial role in maintaining neuronal redox homeostasis by facilitating glutathione synthesis, offering auxiliary antioxidant protection, activating comprehensive stress defense systems, and coupling with energy metabolism
(I) The relevant mechanisms involved in each step of the intracellular GSH exhaustion process need to be further explored, and the biological effect of cancer cells after GSH depletion remains to be elucidated
Abstract Cancer represents the main cause of death worldwide