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The SURMOUNT-1 trial showed that tirzepatide produces dose-dependent weight reduction of 15% to 22.5% over 72 weeks in patients with obesity

A small randomized pilot trial reported a benefit as an add-on in Parkinsons, but the broader epidemiology is mixed and some diabetic cohorts link long-term high-dose use to higher Parkinsons risk

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Aim to consume a minimum of 2 liters of water daily post-treatment to facilitate the efficient elimination of these dissolved fats

making the drug more accessible to a larger number of patients with type 2 diabetes mellitus in the country

GLP-1 agonists bring about similar degrees of weight loss regardless of psychiatric status, but there are reasons to think obesity is different in patients with psychiatric disorders