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Proven benefits of NAC At this time, there is only one scientifically proven benefit of NAC: Treatment of acetaminophen overdose

Athletes and active individuals find that it aids faster recovery, making it easier to return to training or activity

literature identified from PubMed/MEDLINE, Embase, Web of Science, and Cochrane Library (January 2000August 2025)

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Biol Trace Element Res (2015) 167(2):22535

Furthermore, polymorphisms in the BDNF antisense (BDNF-AS) genespecifically rs925946, rs1519480, and rs10767658show significant associations with chronic tinnitus, with rs10767658 conferring a 2.33-fold increased risk in the recessive model and demonstrating associations with tinnitus duration (Yuksel et al., 2023)