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Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins

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Berberine-induced SCFA production, SCFA causes GLP-1 secretion from the intestinal L-Cell." Curcumin - "These findings demonstrate the biological function of curcumin as a GLP-1 secretagogue and the possible molecular target that mediates GLP-1 secretion." Bitter Melon (Momordica charantia) stimulates bitter receptors that stimulate release of GLP-1 and has antidiabetic properties