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doi:10.1016/0003-9861(90)90563-E

Results Cryo-EM structure determination of OCTN2 To determine the structure of OCTN2, we overexpressed full-length human OCTN2 in HEK293F cells and isolated the transporter using a GFP-nanobody purification strategy 28

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Conversely, in the fasted or low-energy state, falling leptin levels relieve the tonic inhibition on AgRP/NPY neurons while simultaneously failing to activate POMC neurons

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