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However, both the baseline permeability and permeability after the addition of gliadin were higher and the luminal zonulin release was more pronounced and prolonged in patients with CeD

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These various confounding factors are quite common in case-control studies and may lead to biased results

Developmental changes in neonatal mice and different routes of drug administration may explain the differences in PK profiles observed in our study compared to previously reported PK profiles in adult mice