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Mitochondria are not only the primary source of ATP but also participate in regulating apoptosis, calcium homeostasis, ROS generation, and immune responses (Qi et al., 2024) (Table 1)

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Their functional enrichment analyses linked these genes to mRNA metabolic processes, immune cell regulation, and RNA transport pathways, confirming their potential role in OA pathogenesis and immune-mediated joint degradation (Huo et al., 2025)

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Lactic Acid Bacteria (LAB) Several Lactobacillus and Bifidobacterium species have demonstrated the ability to bind or reduce certain mycotoxins in experimental models