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High levels of TMAO get linked to an increased risk of atherosclerosis, a disease that clogs your arteries

It was first isolated in 1974 from the cerebral venous blood of rabbits in a sleep state by Monnier and colleagues, making it one of the earlier identified endogenous neuropeptides associated with sleep-wake cycle regulation research

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10.1038/nrm3735 35 MendelsohnC.GouldG

While antibiotics taken for a short time are safe, long-term use can likely affect a mans fertility

Ethics statement The animal study was reviewed and approved by the Ethics Committee for Animal Experimentation of the State University of Maring