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Multivariable linear regression analyses were performed to evaluate independent associations between treatment group and primary outcomes (% weight loss and HbA1c reduction at 6 months), adjusting for age, sex, baseline BMI, baseline HbA1c, and hepatosteatosis grade

The article treats those as genuine trade-offs rather than a ranking

Because muscles burn more calories and require more energy than fat, changes in muscle mass are common

doi: 10.1093/ajcn/39.5.722.[PubMed] Sies H (1999)

Abdullah builds transition planning into the program from the start using the medication course to optimize the hormonal and metabolic foundation, establish behavioral patterns, and evaluate candidacy for maintenance or step-down protocols

15% body weight reduction)