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Counsel patients that GI side effects (nausea, vomiting) during GLP-1 RA titration could impair oral contraceptive absorption through vomiting-related missed doses, and recommend a backup method during the first 4 weeks of titration if vomiting occurs

Reported across doses, often related to reduced food intake during the stepping-up phase

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These are unique non-metformin-based FDCs, which is why there is no clear guidance on their place in T2DM management

GLP-1 injections are administered subcutaneously, just under the skin, so the ideal areas have enough fatty tissue and are easy to reach

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