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Lim JU, Lee J-H, Kim T-H, Lee JS, Lee S-D, Oh Y-M, Rhee CK
Karampatakis T, Tsergouli K, Behzadi P
2011;300(6):H2054H2063
However, control mice exhibited the expected 2DG-induced hyperphagia 22 , while this response was prevented in AgRP GHR KO mice (Fig
Conclusion: NPs and antitumor compounds demonstrate therapeutic potential against MM through multi-dimensional ferroptosis modulation, yet clinical translation faces two critical hurdles: 1) predominant focus on single-target mechanisms lacking systems pharmacology-level network analysis
The doses chosen were because higher doses of cagrilintide may be associated with gastrointestinal adverse effects, in particular nausea and vomiting, and require dose escalation to be attained
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