No matter how you are losing weight, whether its through medication or lifestyle interventions, your body will adapt over time
Serious adverse effects requiring clinical vigilance include: Lactic acidosis : A rare but potentially fatal complication of metformin, particularly in patients with renal impairment (eGFR 10%), symptomatic hyperglycemia, diagnostic uncertainty, or recurrent hypoglycemia
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Journal of Korean Medical Science, 25(5), 776-780
Because they may be situational, identifying and avoiding triggers may help patients prevent them
further emphasized that only 40% of patients received guideline-based OA management, such as the better management of patients with osteoarthritis program, before being placed on a surgical waitlist, with even fewer receiving such care during the wait, underscoring systemic deficiencies in guideline implementation (Cronstrm et al., 2020)