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T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8

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1.4.4 MDT review of variant prioritization For the preparation of the genetic results report, the workflow relies again on the MDT, which at this step includes at least two clinical geneticists, a bioinformatician, a molecular biologist, a pharmacogenomics specialist, and a precision medicine expert

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RosenstockJAllisonDBirkenfeldALBlicherTMDeenadayalanSJacobsenJBet al

Santos JX, Rasga C, Marques AR, Martiniano H, Asif M, Vilela J, Oliveira G, Sousa L, Nunes A, Vicente AM (2022) A role for gene-environment interactions in autism spectrum disorder is supported by variants in genes regulating the effects of exposure to xenobiotics