These include other GLP-1 receptor agonists like liraglutide (Victoza) and dulaglutide (Trulicity), GLP-1/GIP RAs like tirzepatide (Mounjaro), as well as other classes of medications such as sulfonylureas, thiazolidinediones, and SGLT2 inhibitors
No human approval: there are no official human guidelines, because the compound is unapproved
Because authentic GLP-1 analogs are prescription-only drugs requiring medical supervision, any over-the-counter patch claiming equivalent results should be viewed with skepticism
Considering that GLP-1R agonists are FDA approved drugs to treat T2DM and also ameliorate NASH, in the present study we evaluated the efficacy of a GLP-1R agonist in two mouse models: one model with NASH-like features (methionine and choline-deficient (MCD) diet), and a second high-fat model of metabolic syndrome and hepatic dysfunction
[DOI] [PubMed] [Google Scholar] Polonsky KS
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