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#ADA2025: Eloralintide vs Cagri in Rats Selective amylin mimetic shows improved tolerability and lean mass preservation Preclinical head-to-head in lean & DIO rats Eloralintide: Similar weight loss to Cagri Less conditioned taste aversion Lowered fat mass with lean mass sparing Modified with C20 tail for longer action GI tolerability and quality of weight loss favoured Elora vs Cagriwell at least in Supports ongoing clinical dev as a selective amylin agent Poster 849-P #Obesity #Amylin #Eloralintide #Cagrilintide #Preclinical #ADA2025 #ADA2025: Eloralintide vs Cagri in Rats Selective amylin mimetic shows improved tolerability and lean mass preservation Preclinical head-to-head in lean & DIO rats Eloralintide: Similar weight loss to Cagri Less conditioned taste aversion Lowered fat mass with lean mass sparing Modified with C20 tail for longer action GI tolerability and quality of weight loss favoured Elora vs Cagriwell at least in Supports ongoing clinical dev as a selective amylin agent Poster 849-P #Obesity #Amylin #Eloralintide #Cagrilintide #Preclinical #ADA2025
Not Suitable For: Infants
10.1016/s0305-4179(03)00004-4 122 SikiricP.SeiwerthS.RucmanR.DrmicD.StupnisekM.KokotA.et al (2017)
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As a modified fragment of human growth hormone (hGH), this peptide focuses on fat metabolism without the typical side effects associated with full hGH therapy, such as insulin resistance or increased IGF-1 levels
