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Nonetheless, two IV studies have been published related to Parkinsons disease, one open-label which found significant improvement and a slowing of the disease, and one randomized and double-blinded which found only mild symptomatic improvement

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doi: 10.3390/ijms24032440 241 SakazakiFArakawaTShimizuROginoHOkunoTUenoH

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2.2.1 Initiation and progression of neurodegenerative diseases Each neurodegenerative disease has distinct initiating pathological proteins and vulnerable neuronal populations, but a common theme is that the accumulation of protein aggregates and resulting neuronal stress elicits a sustained immune response in the brain