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Any way you slice it, its a quarter of your total body weight, said Dr Caroline Apovian, who treats obesity at Brigham and Womens Hospital in the US state of Massachusetts, who wasnt involved in the study

Many users report feeling benefits within a few days to a couple of weeks, but individual responses may vary

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Insufficient Dosing and Tolerance Barriers Many people fail to reach an effective dose because they experience gastrointestinal side effects like nausea, constipation, or delayed gastric emptying during the titration phase

In addition, it can be bound to proteins and other thiols, affecting their activity