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Selection criteria were the RNA integrity number (RIN) from the Agilent Bioanalyzer system, which measures RNA quality and distance from the other replicate samples in principal component analysis (PCA) or multi-dimensional scaling (MDS) plots

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Mazdutide is structurally based on oxyntomodulin, a naturally occurring peptide produced by intestinal L-cells that activates both GLP-1 and glucagon receptors

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