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Indeed, the hypomethylation of CD40L in T cells has also been associated with increased disease activity in SLE patients (196, 197)

Full model: Adjusted for sex, age, inclusion date, diabetes duration, Charlson Comorbidity Index, any diabetic complications, previous falls, inflammatory bowel disease, ever insulin use, ever glucocorticoid use, hypertension, kidney disease, alcohol, smoking and obesity, and stratified by osteoporosis