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If you want long-lasting results, limiting or avoiding both is best

Hemoglobin oxidation at functional amino acid residues during routine storage of red blood cells

Additionally, nanoencapsulation ensures controlled, prolonged release, enhancing both local and systemic effects and confirming the effectiveness of these techniques in experimental models [63]

In animal-based foods, vitamin B12 binds to the protein molecules

Effects of vitamin B12 supplementation on cognitive function, depressive symptoms, and fatigue: a systematic review, meta-analysis, and meta-regression

While this allows very elegant applications such as the generation of 3D structures in hydrogels, the SpyLock approach is much easier to implement and more economical to scale as it does not require an expression system capable of incorporating artificial amino acids