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2: 12536 Acknowledgements The author thanks Sigma-Tau SpA for its financial support

Ghrelin is responsible for several anabolic processes in the body including [2]: Energy usage Appetite suppression Fat processing As a ghrelin mimetic, ipamorelin significantly influences the GI system, body composition, and adiposity

In addition, for example, they reduce incidence of cold sores, strengthen weak venous walls, and are therefore often used in haemorrhoids, varicose veins, bleeding gums, etc

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This information is key for identifying pathway-biased agonists that avoid beta-arrestin-mediated side effects (e.g., tolerance), thereby supporting lead optimization and selection of safer, more efficacious candidates before preclinical studies

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