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The gut microbiota is metabolically highly active and it produces a range of different compounds, including neuroactive molecules, such as acetylcholine, catecholamines, -aminobutyric acid, histamine, melatonin, and serotonin

Historically, this led many researchers to believe that oral glutathione was essentially useless

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Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice