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doi: 10.1002/(SICI)1521-4141(199904)29:04 3.0.CO;2-C 76 ChangJChoJHLeeSWChoiSYHaSJSungYC

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The evidence for glycine preventing muscle loss during GLP-1 therapy is limited, but the amino acid is safe at the doses included in these formulations

The post points to rapid weight loss with loss of lean tissue, shifts in sodium, potassium and magnesium, dehydration when nausea suppresses thirst, reduced caloric and protein intake, and increased physical activity as energy improves