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In a retrospective cohort study of Taiwanese patients with concurrent asthma and diabetes from 2001 to 2011 they looked at metformin-prescribed patients 1:2 versus non metformin users corrected for age and gender over 3 years

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This may lead to enhanced binding of inhibitors to other proteins

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How GIPR and GLP-1R Signals Converge Intracellularly Both receptors raise cAMP, but they do so in different cell compartments and with different kinetics, which matters for signaling crosstalk