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Moreover, the gut-selective dose of sitagliptin was unable to lower TG excursion in HFD-fed Dpp4 EC+/+ and Dpp4 EC/ mice, before and after BMT, despite an approximately 20% reduction in plasma DPP-4 activity and an increase in active GLP-1 (Figure 7)

Aim for consistent water intake throughout the day, and be mindful that GLP-1 medications can blunt thirst cues

If you use a CGM, you may notice fewer steep rises after meals and more time spent in your target range even before your insulin doses are fully adjusted

Clinical data shows that side effects often decrease as your body adapts to the medication over weeks and months

Zerbinati C, Caponecchia L, Rago R, et al

Safety considerations and precautions Generic Ozempic is generally safe when used as prescribed and under proper medical supervision