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The risk becomes clinically meaningful primarily in people with diagnosed low blood pressure, particularly those taking blood pressure-lowering medications or managing conditions like orthostatic hypotension
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When a study engages in questionable research practices (QRPs) and ignores these previously detailed, scientifically determined hazards of the premature administration of pimobendan (over-stimulating the well-compensated heart's contractility), and instead the study is based upon superficial appearances (a heart's linear dimensions exceeding arbitrary minimums), that study can easily lead to false positives
As long as the vacuum seal remains intact, the powder remains completely sterile, dry, and safe for research use