Potential Side Effects, Contraindications, and Safety Questions GLP-1 medications have a well-documented safety profile, and it's worth knowing it before you start - not after your first injection
Functional brain imaging studies have reported a decrease in synaptic connectivity and neuronal circuitry in the PFC and hippocampus in depressed patients (Perlman et al., 2012
277,278,279,280 This effect is accomplished through the inhibition of JNK, NF-B, and other relevant signaling pathways
The ideal rate of weight loss for hair preservation Most dermatologists and endocrinologists recommend a weight loss rate of one to two pounds per week, or roughly 0.5-1% of body weight per week, to minimize the risk of telogen effluvium
Physiological adaptations to weight loss and factors favouring weight regain
However, anti-obesity medications are prescribed to only about 4% of eligible people due to concerns about safety or effectiveness, lack of health care provider training in weight management, excessive costs due to insurance companies refusing coverage, and a toxic stigma that portrays obesity as a lack of willpower
