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Another group reported that the synbiotics supplements, which contained 100 mg Lactol probiotic comprised of Lactobacillus coagulants and Fructo-oligosaccharides (FOS) administered to hemodialysis patients in a randomized, double-blind, placebo-controlled trial significantly reduced total iron binding capacity in the synbiotic group

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doi: 10.1002/biof.5520100227 143

This QC sample was plated at different positions on the 96-well plate and injected six times to calculate the coefficient of variation (CV) for data quality control, and undetectable metabolites were excluded from the analysis