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CAR-T cells targeting B7-H3 are also effective in inhibiting growth in vitro and in vivo of NSCLC (158), prostate cancer (159), glioblastoma (116), ovarian and triple negative breast cancer (160)

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[4] In the SURMOUNT-1 obesity trial, a 72-week placebo-controlled study in 2,539 adults with obesity (without diabetes), mean weight change was 15.0%, 19.5%, and 20.9% at the 5, 10, and 15 mg doses versus 3.1% for placebo

Besides, as shown in Figure 4, this article included different subgroup analyses (intervention duration, dosage form, health condition, and BMI), and the heterogeneity was above 90%

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