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Diabetes Care 29, 15541559 (2006)

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So it can cause organ damage and peripheral neuropathy, diabetic retinopathy

Retatrutide is investigated as a unimolecular agonist that engages three complementary incretin and glucagon pathways simultaneously, with research interest in body composition, hepatic lipid metabolism, glycemic endpoints, and energy expenditure in obesity and metabolic disease models

However, based on mechanistic understanding and data from similar medications, theres no evidence of permanent metabolic impairment

Emerging evidence highlights taste and olfactory disturbances as underrecognized NAEs of GLP-1 RA therapy 44,45,46