The December 2025 Phase 3 TRIUMPH-4 results were even more impressive, with the 12mg group losing an average of 28.7% of body weight over 68 weeks
Reduced caloric and protein intake Hair follicles need amino acids (particularly keratin-building proteins) to thrive
The result is more of a wellness patch than a medical treatment
Microdosing, a so-called wellness trend thats gained popularity in recent years, typically involves taking small amounts of psychedelic drugs to improve mental health or boost focus and creativity
Secondary outcomes included nonfatal MI, nonfatal stroke, HHF and renal composite outcome, defined in most trials as a composite of progression to end-stage renal disease or a sustained decrease of at least 40% in estimated glomerular filtration rate (eGFR)
The top concern is the lack of research on the effectiveness or safety of microdosing the drugs (or using GLP-1s, period) in people with normal weight and blood sugar