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Besides their GPCR nature and the associated implications for drug discovery, one of the most interesting aspects of the melanocortin system ( Figure 2 ) that makes it very attractive for the development of new therapies is the remarkable functional specialization of the MC receptors, controlling multiple and diverse processes around the body, including skin pigmentation and DNA repair, appetite regulation, blood pressure, production of cortisol, regulation of glands secretions, and immune responses, among others (159)

Additionally, for ebselen to become a clinically acceptable radioprotector, there is also a need for establishing its selective radioprotective effects without compromising the tumor radiosensitivity

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Both should be discussed with a doctor, but liposomal glutathione is often preferred for its direct impact on antioxidant levels