mechanism of action glp 1 Frontiers New research identifies a mechanism

MS contributed in writing the manuscript and in conceiving and creating the figures

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Inhibition of glucagon secretion or antagonism of glucagon receptors has become a potentially effective treatment strategy for T2DM patients (Lund et al., 2014)

363 Reduced activity and expression of the GLUT-1 transporter in the BBB suggest decreased glucose uptake and utilization by the brain, 360,363 which may further exacerbate cerebrovascular degeneration, BBB breakdown, and A pathology in models overexpressing APP, inducing neurodegeneration and cognitive deficits (Fig

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In order to minimize elevated spikes in the after meals state throughout the day, it is imperative to take into account the dietary content of each meal separately (92) (Grade C)