The first use of a GLP-1 drug for weight management was not approved by the U.S
There is no clinical evidence supporting any interval other than once weekly
A composite analysis of 8 cardiovascular outcomes trials completed in 2021 demonstrated reduced incidence of major cardiovascular events by 14% and cardiovascular death by 13% (NCT01147250, NCT01179048, NCT01720446, NCT01144338, NCT02465515, NCT01394952, NCT02692716, NCT03496298)
However, there is a considerable chance of long-term side effects after surgery
See what people said after trying this 7-day GLP-1 meal plan Frequently Asked Questions Should I eat before my GLP-1 injection
For other Novo Nordisk medications, the threshold is 400% FPL (about $60,240 single)