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And let's be honest - not everyone is comfortable injecting themselves with anything in the first place

A potential mechanism is emperiopolesis

Mottillo EP, Desjardins EM, Fritzen AM et al (2017) FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis

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GLP-1 drugs like Ozempic, Wegovy and Mounjaro delay gastric emptying, increasing the risk for pulmonary aspiration

The nitrites can also interact with other protein components to form N -nitroso compounds, a powerful class of carcinogens found in cigarette smoke