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In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

Impairment of peripheral nerve regeneration by insufficient activation of the HGF/c-Met/c-Jun pathway in aged mice

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Front Pharmacol 15:1531288