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Cell 155 , 14221434 (2013)
A recent clinical trial found that adding the glucagon-like peptide 1 (GLP-1) drug tirzepatide to the biologic ixekizumab helped 30 percent of adults with active psoriatic arthritis (PsA) who had overweight or obesity better control their symptoms while also losing weight
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External standard libraries were used to confirm the m / z and retention time for each metabolite
This spikes blood sugar, worsens insulin resistance, and can increase nausea
With the recognition that adult humans also have BAT, an organ with substantial capacity to dissipate energy, BAT gained considerable interest as a novel target to treat or prevent obesity and its associated diseases
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