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Under the GLP-1 Bridge Program, Medicare will cover Wegovy specifically for weight loss - not just for diabetes management

An exploratory DEXA substudy of the STEP 1 trial (140 participants, 68 weeks) found that semaglutide 2.4 mg produced a 19.3% reduction in total fat mass and a 9.7% reduction in total lean body mass with the proportion of lean mass relative to total body mass actually increasing by 3.0 percentage points because fat was lost more rapidly. These results were exploratory and not corrected for statistical multiplicity, so they should be interpreted accordingly

& McNeill, J

Mijailovich et al., 2021

The two get lumped together constantly, yet they are not really rivals, and treating the choice as a winner take all contest usually leads to the wrong plan

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