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The findings of the REDEFINE 1 and REDEFINE 2 trials reinforce the pivotal role of combination pharmacotherapy by targeting diverse mechanisms of action that translate into improved weight loss achievements as well as an impact on complications

Moreover, it is more effective than dulaglutide in diminishing fasting glycemia

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Green circles indicate the measured JWST photometry, while pink triangles indicate upper limits from Gaia, 2MASS, Spitzer/IRAC and Spitzer/MIPS

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