Common symptoms of a lower urinary tract infection (cystitis) include: A persistent, strong urge to urinate A burning sensation or pain when passing urine (dysuria) Passing frequent, small amounts of urine Cloudy, dark, or strong-smelling urine Blood in the urine (haematuria), which may appear pink or red Pelvic discomfort or pressure, particularly in women A feeling of incomplete bladder emptying Upper urinary tract infections (pyelonephritis) , affecting the kidneys, are more serious and may present with additional symptoms such as high fever, chills, nausea, vomiting, and pain in the back, side, or groin
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The incidence of nausea and vomiting was substantially reduced with dose escalation
The dual role of ROS as signaling molecules and potential toxins emphasizes their importance in maintaining oxygen homeostasis and their involvement in disease pathogenesis when dysregulated [545]
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Stability degrades significantly if exposed to room temperature for more than 2 hours cumulatively or if frozen after reconstitution freezing causes ice crystal formation that disrupts protein structure