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Why on earth would any one with half a brain think that a high or a low folate concentration negates the need for B12 when the serum B12 level is low

Firstly, the N-terminal domain recognizes and binds the substrate in a non-ATP-dependent manner

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It upregulates genes involved in repair, antioxidant defense, and stem cell function while downregulating genes associated with inflammation, fibrosis, and tissue destruction

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