2.4% with placebo [8]
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With the right strategiesgradual dose escalation, dietary modifications, adequate hydration, and when needed, anti-nausea medicationsmost people can successfully manage this side effect and continue benefiting from these powerful medications
Nausea typically begins appearing during this period, though it remains mild for most people
A person who tolerates 8mg with zero side effects and achieves 21% weight loss over 48 weeks has a better outcome than someone who pushes to 12mg, feels terrible for three months, and quits at week 16
Cytokine involvement in migraine has been extensively studied, particularly TNF- and IL-1